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tolbutamide and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

tolbutamide has been researched along with (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	1 (33.33)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Appel, S; Hitzenberger, G; Kalafsky, G; Kallay, Z; Kutz, K; Rüfenacht, T; Tetzloff, W	1
Andersson, TB; Bredberg, E; Ericsson, H; Sjöberg, H	1
Hsiong, CH; Hu, OY; Lee, MS; Pao, LH; Shih, TY; Wang, HJ	1

Trials

2 trial(s) available for tolbutamide and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

Article	Year
Lack of interaction between fluvastatin and oral hypoglycemic agents in healthy subjects and in patients with non-insulin-dependent diabetes mellitus. The American journal of cardiology, 1995, Jul-13, Volume: 76, Issue:2 Topics: Administration, Oral; Anticholesteremic Agents; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diclofenac; Drug Interactions; Fatty Acids, Monounsaturated; Fluvastatin; Glyburide; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Insulin; Lovastatin; Placebos; Simvastatin; Tolbutamide	1995
An evaluation of the in vitro metabolism data for predicting the clearance and drug-drug interaction potential of CYP2C9 substrates. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:7 Topics: Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cross-Over Studies; Cytochrome P-450 CYP2C9; Diclofenac; Drug Interactions; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Ibuprofen; In Vitro Techniques; Indoles; Male; Mass Spectrometry; Microsomes, Liver; Middle Aged; Tolbutamide	2004

Article

Year

Lack of interaction between fluvastatin and oral hypoglycemic agents in healthy subjects and in patients with non-insulin-dependent diabetes mellitus.

The American journal of cardiology, 1995, Jul-13, Volume: 76, Issue:2

Topics: Administration, Oral; Anticholesteremic Agents; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diclofenac; Drug Interactions; Fatty Acids, Monounsaturated; Fluvastatin; Glyburide; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Insulin; Lovastatin; Placebos; Simvastatin; Tolbutamide

1995

An evaluation of the in vitro metabolism data for predicting the clearance and drug-drug interaction potential of CYP2C9 substrates.

Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:7

Topics: Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cross-Over Studies; Cytochrome P-450 CYP2C9; Diclofenac; Drug Interactions; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Ibuprofen; In Vitro Techniques; Indoles; Male; Mass Spectrometry; Microsomes, Liver; Middle Aged; Tolbutamide

2004

Other Studies

1 other study(ies) available for tolbutamide and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

Article	Year
Dietary flavonoids modulate CYP2C to improve drug oral bioavailability and their qualitative/quantitative structure-activity relationship. The AAPS journal, 2014, Volume: 16, Issue:2 Topics: Administration, Oral; Animals; Biological Availability; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diet; Disaccharides; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Flavonoids; Fluvastatin; Indoles; Male; Microsomes, Liver; Quantitative Structure-Activity Relationship; Quercetin; Rats; Rats, Wistar; Tolbutamide	2014

Article

Year

Dietary flavonoids modulate CYP2C to improve drug oral bioavailability and their qualitative/quantitative structure-activity relationship.

The AAPS journal, 2014, Volume: 16, Issue:2

Topics: Administration, Oral; Animals; Biological Availability; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diet; Disaccharides; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Flavonoids; Fluvastatin; Indoles; Male; Microsomes, Liver; Quantitative Structure-Activity Relationship; Quercetin; Rats; Rats, Wistar; Tolbutamide

2014